Underwood Center forDigestive Health
Digestive Health
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Quarterly Digest
In September, Professor Sir Pali Hungin, MD, delivered the 2024 Underwood Presidential Lecture: “The Changing Face of Medicine: Visualizing the Future” on the future of medicine and the role of the physician. Dr. Hungin shared his career experience as a primary care physician and academic in the northeast of the UK. In his wide-ranging and highly relevant lecture, he touched upon several areas where doctors will be challenged via the impact of social media, the benefits and pitfalls of the EMR, and our possible replacement by AI. I urge you to listen to his lecture in its entirety, which has been archived here. In the end, I had to ask myself: what will the Underwood Center look like in years to come and are we prepared for these challenges? It’s a lot to think about.
I believe that, whether by design or happenstance, we are in pretty good shape. Thanks to COVID, hybrid or all-virtual conferences and meetings are the new normal and have increased attendance at many of our clinical and educational events. The Friday Multidisciplinary GI Conference, our Annual Underwood Symposium and Professor Sir Hungin’s lecture all illustrate enhanced audience participation thanks to the availability of streaming. These platforms are especially valuable in a center as geographically dispersed as ours. We continue to participate in virtual consultations with our patients and, while the future of this approach lies in the hands of those who pay the bills, there is no doubt that it can play a valuable role in patient care. Ongoing work on uploading motility studies, from any HM clinical location to the cloud where they can be viewed and interpreted by experts located elsewhere, is a more specific example of how Underwood is taking advantage of the digital age to optimize patient care. I confess to being a neophyte when it comes to AI, but I can see its potential in facilitating the type of big data research we hope will emanate from an Underwood Research Network and Houston Methodist Research Institute scientists and clinicians who are already active in this area.
I am impressed that Houston Methodist is aware of the challenges and opportunities that new technologies present and will be ready to adopt all that is valid and pass on what is not. Our task is to be ready to grasp opportunities and deal with the challenges that this new age of medicine presents.
Eamonn M.M. Quigley, MD
David M. Underwood Chair of Medicine in Digestive Disorders
Co-Director, Lynda K. and David M. Underwood Center for Digestive Disorders
Chief, Gastroenterology and Hepatology, Houston Methodist Hospital
Professor of Medicine, Weill Cornell Medicine
Adjunct Professor of Medicine, Texas A&M Health Sciences Center College of Medicine
With the New Year approaching, we have been working hard in the Underwood Center to ensure continued excellence in our programs and innovative planning for next year.
Our quality reviews demonstrate a continuation of excellent surgical results, with our superb safety maintained throughout 2024. We have made additional studies in expanding our colorectal volume and are hoping to initiate a Methodist Colorectal training program in the next year.
Preparation for the start of the Pancreas Cyst Clinic as part of the Pancreas Surgery Program is ongoing with the acquisition of all data on pancreatic procedures and continued expansion of the Pancreas Registry. We are confident that this registry will be our springboard to expanding pancreatic surgery and extending more innovation into pancreatic procedures.
Finally, we are planning a multidisciplinary planning meeting for a new program for Metabolic Management and Weight Loss.
A. Osama Gaber, MD, FACS, FAST
John F., Jr. and Carolyn Bookout Presidential Distinguished Chair in Surgery,
Department of Surgery
Chair, Department of Surgery
Professor of Surgery, Academic Institute
Full Member, Research Institute
Program Director, Transplant Surgery Fellowship, Department of Surgery
Houston Methodist
Weill Cornell Medical College
Eamonn Quigley, MD, participated in a discussion group on the microbiome-gut-brain axis and neurodevelopmental and neurodegenerative disorders at the International Scientific Association for Probiotics & Prebiotics (ISAPP). The presentations featured ASD, MS, PD, ADHD and mood disorders.
In August, Sunil Dacha, MD, served as a course director for the American Society for Gastrointestinal Endoscopy (ASGE) First Year Fellows Endoscopy Course.
On October 10, Eamonn Quigley, MD, presented at the American College of Gastroenterology (ACG) virtual grand rounds, “First Do No Harm: How to Approach the Patient with GI Symptoms Overlapping with EDS, POTS & MCAS,” a subject of increasing significance to gastroenterologists. Click here for PDF presentation.
Monitoring Trough Levels of VDZ Helps Accuracy in Patient Dosage
Researchers at the Lynda K. and David M. Underwood Center found that monitoring Vedolizumab (VDZ) trough levels can improve treatment outcomes for ulcerative colitis and Crohn’s disease. Higher VDZ levels are linked to better results, indicating that adjusting dosing frequency may be beneficial for patients with low troughs. The team emphasizes the potential of new therapies to enhance patient quality of life and reduce surgery rates.
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Innovations Continue for Treatment of Obesity
Thomas R. McCarty, MD, MPH, is transforming obesity treatment at Houston Methodist with an innovative bariatric endoscopy program that pairs minimally invasive techniques with injectable weight-loss medications, achieving results similar to traditional surgery. His new clinical trial will explore a one-time endoscopic treatment to improve blood sugar control for patients with obesity and diabetes. This comprehensive approach aims to reduce the risk of weight regain and provide tailored solutions for better health outcomes.
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GERDing Against Poor Lung Transplant Outcomes
Gastroesophageal reflux disease (GERD) poses a significant challenge for lung transplant recipients, with up to 75% affected. While fundoplication surgery can alleviate GERD symptoms by reinforcing the esophagus-stomach connection, studies suggest lung transplant patients may face complications and hinder recovery post-surgery.
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Can Liver Transplants Spread COVID-19?
A recent study led by Ashton Connor, MD, PhD, reveals that using livers from COVID-19-positive donors poses no significant risk to transplant recipients. Analyzing over two years of data, the research challenges fears about virus transmission, highlighting the need for continued vigilance in organ donation practices. These findings provide crucial insights as the demand for liver transplants surges amid the pandemic.
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How Diet Can Change the Course of GI Disease
Eamonn Quigley, MD, reveals that diet can dramatically alter the trajectory of gastrointestinal diseases. In his recent study, published in the Journal of Gastroenterology and Hepatology, the findings highlight how dietary management is crucial in conditions like food allergies, eosinophilic esophagitis, and celiac disease. Discover how what you eat could reshape your gut health and the future of GI disease management.
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View our comprehensive list of clinical trials for IBD, GERD, liver and more. We invite current Underwood Center members to submit their clinical studies to be spotlighted in upcoming newsletters.
Prevalence of Steatotic Liver Disease (MASLD, MetALD, and ALD) in the United States
Kalligeros, M, Vassilopoulos, A, Vassilopoulos, S, Victor, DW, Mylonakis, E & Noureddin, M 2024
https://doi.org/10.1016/j.cgh.2023.11.003
Critical appraisal of the SIBO hypothesis and breath testing: A clinical practice update endorsed by the European society of neurogastroenterology and motility (ESNM) and the American neurogastroenterology and motility society (ANMS)
Kashyap, P, Moayyedi, P, Quigley, EMM, Simren, M & Vanner, S 2024
https://doi.org/10.1111/nmo.14817
Post Operative Pain Control Following Colon Resection - and the Pendulum that has Swung from One Extreme to the Other
Mahmood, A., Yaakovian, M., Ahmed, K., & Mahmood, A. M. (2024).
https://doi.org/10.14738/bjhmr.115.17714
American College of Gastroenterology Annual Scientific Meeting and Post-Graduate Course 2024
In October, the GI Division presented more than 20 abstracts and poster presentations at the American College of Gastroenterology’s (ACG) Annual Scientific Meeting and Postgraduate Course in Philadelphia, Penn. Faculty, fellows, and medical students gave over 20 oral and poster presentations and taught hands-on courses. Houston Methodist’s contributions to the meeting included an oral presentation on resmetirom efficacy on the treatment of adults with noncirrhotic non-alcoholic steatohepatitis (NASH) by Mazen Noureddin, MD, MHSC, and a hands-on course on hemorrhoid management by Neha Mathur, MD. There was a variety of posters covering a range of topics from drug therapies for Crohn’s disease to useful electronic apps and technology in the management of chronic idiopathic constipation. Eamonn Quigley, MD, and Bincy Abraham, MD, MS, also hosted an ACG social hour for Houston Methodist colleagues and friends, and presented the Alberto O. Barroso, MD award to third year fellow Usman Ansari, DO for research excellence.
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Presidential Seminar Series – The Changing Face of Medicine
Professor Sir Pali Hungin recently delivered a thought-provoking lecture on the future of medicine, drawing significant attendance and engagement from medical students and practicing physicians across various specialties. As the lead of the Changing Face of Medicine commission by the UK Academy of Medical Royal Colleges, Hungin explored the profound societal and technological shifts reshaping the role of doctors, including the evolving patient-clinician relationship, advances in AI, and the importance of clinician wellbeing and leadership. His presentation raised critical questions about the future of the medical profession, challenging attendees to consider whether doctors, as we know them. will exist in 20 years. Click here to watch.
Click on each thumbnail to enlarge the photo.
Emerging Topics in Liver Disease Conference:
Innovative Trends in Liver Health 2024
On September 21, Victor Ankoma-Sey, MD, FACP, FAASLD and the Sherrie and Alan Conover Center for Liver Disease and Transplantation hosted the Emerging Topics in Liver Disease Conference at Houston Methodist’s Research Institute. This continuing education activity was designed to educate attendees about new developments in hepatology and new approaches to management of liver diseases that can be readily integrated into daily practice. A group of national experts, including several renowned guest faculty, presented new findings in a clinical context that are beneficial in the multidisciplinary management of unique and complex liver disorders. Dr. Ankoma-Sey has been hosting this conference in Houston for the past 25 years.
Hepatology Update for Primary Care
In October, Rashid Khan, MD, directed an insightful course, “The Sixth Annual Hepatology Update for Primary Care: A Practical Approach”. The conference highlighted the knowledge gap, which exists within primary care regarding liver disease, while serving to educate on the latest developments and research in this area. The speakers and their topics were as follows:
- Tammneet Basra, MD: “Liver Disease in Pregnancy”
- Chukwuma Egwim, MD: “Alcohol-associated Liver Disease”
- Robert S. McFadden, MD: “Focal Liver Lesions - What the Internist Needs to Know”
- David Victor, MD: “The Culprit bystander in TTR Amyloidosis”
2nd Summit on Gastrointestinal Malignancies, DAVA Oncology
Maen Abdelrahim, MD, PhD, B Pharm and Sudha Kodali, MD, MBBS, were guest faculty at the 2nd Summit on Gastrointestinal Malignancies in Bermuda on September 25-29. Dr. Abdelrahim presented on “Targeting Claudin 18.2 In Pancreatic Cancer” and Immunotherapy Before Transplant in GI malignancies.” Dr. Kodali presented on “Out Criteria HCC Patients Who Could Benefit From Transplantation.”
Houston Methodist Welcomes New Fellows
Advanced Endoscopy Fellowship
Benjamin Walker Warren, MD
Medical School: McGovern Medical School at The University of Texas Health Science Center, Houston, TX
Residency: University of Colorado, Aurora CO
Gastroenterology Fellowship: HMH
Inflammatory Bowel Disease Fellowship
Megan E. Lewis, DO
Medical School: University of North Texas Health Science Center Texas College of Osteopathic Medicine, Fort. Worth, TX
Internal Medicine Residency: The University of Texas Health Science Center San Antonio Joe and Teresa Lozano Long School of Medicine Program, San Antonio, TX
Gastroenterology Fellowship: Texas A&M College of Medicine - Baylor Scott & White Medical Center, Temple, TX
IBD Fellowship: Houston Methodist Hospital
Partnering with Local Organizations to Discuss Gut Health
Through community partnerships, we are able to support initiatives that have a real and meaningful impact on the lives of people right here in our community. Houston Methodist The Woodlands Hospital is a proud supporter of Junior League of The Woodlands and included the topic “Gut Wellness: Understanding Digestive Health” as part of a Houston Methodist Education Series to equip participants with practical knowledge and strategies to promote a healthy gut. Hassan Dakik, MD, who has recently joined Houston Methodist West, led the conversation to explore the intricate workings of the digestive system and explore how gut health impacts overall wellbeing. With 69 attendees for this virtual event, it was a very engaging topic and interactive conversation. Click here to watch the recording.
Houston Methodist Hospital
In August, Houston Methodist welcomed thoracic surgeon Warren Naselsky, MD, to the Division of Thoracic Surgery in the Department of Surgery, who is excited to contribute to the management of patients with both benign and malignant diseases of the esophagus and foregut, including esophageal cancer, achalasia, gastroesophageal reflux, and hiatal hernia. HM is truly leading medicine in esophageal cancer treatment with its advanced robotic esophagectomy program. Surgeons in the Division of Thoracic Surgery have completed more than 150 robotic esophagectomies, establishing the hospital as a pioneer in minimally invasive surgery. This technique results in quicker recovery and reduced complications for patients.
Houston Methodist Clear Lake
Houston Methodist Clear Lake highlights Valentine O. Millien, MD, Ahmed Ali, MD, and Kyle W. Stephens, MD, as Underwood members. HMCL also held their first Digestive Disease Committee meeting on October 1.
Houston Methodist Sugar Land
Gastroenterologist Neel Choksi, MD started at Houston Methodist Sugar Land this month.
Houston Methodist West
With the addition of T. Peter Nguyen, MD in September, Houston Methodist West now has a team of seven gastroenterologists.
Inaugural Houston Methodist Neal Cancer Center GI Oncology Hybrid Symposium
Friday, Dec. 6
8:30 a.m. – 3:15 p.m.
Houston Methodist Research Institute, John F. Bookout Auditorium
6551 Bertner Ave, Houston, TX 77030
PROGRAM CHAIR
Maen Abdelrahim, MD, PhD, PharmB
Associate Professor of Medicine
PROGRAM OVERVIEW
This symposium will delve into the latest developments in managing gastrointestinal cancers. It will feature expert presentations on advancements in immunotherapy, molecular diagnostics, targeted therapies and new surgical techniques. Participants will also explore key trends in transplant oncology and the role of precision medicine. Each session will offer insights into disease pathogenesis, risk factors, prevention strategies, and innovative treatments, including discussions on minimally invasive procedures, enhanced imaging, and blood-based biomarkers. The symposium will emphasize how these advancements improve patient outcomes and provide a comprehensive review of current and emerging management strategies for various gastrointestinal cancers.
Click here to register
Houston Cholangiocarcinoma Symposium
We are so excited to have the Cholangiocarcinoma Foundation facilitating the 2024 Houston Cholangiocarcinoma Symposium in Houston on December 13, 2024, with hosts Dr. Sudha Kodali, Dr. Hop Tran Cao, and Dr. Milind Javle in a joint collaboration with Houston Methodist and The University of Texas MD Anderson Cancer Center.
The symposium will bring together leading experts, researchers, healthcare professionals, patients and advocates with a crucial platform for sharing the latest advancements and addressing the challenges in cholangiocarcinoma research and treatment. Click here for the agenda.
Click here to register
Multidisciplinary GI Conference
Every Friday at 7 a.m.
Led by: Alberto O. Barroso, MD
Presenters:
Nov. 22 - Dr. Ali Raza/ Ronan Allecherril
Dec. 6 - Dr. Lee Morris
Dec. 13 - Dr. Christopher Fan/ Dr. Raj Waghela
Dec. 20 - Dr. Kelvin Allenson
Contact: Alessandra Rodriguez for more information.
Monthly IBD Case Conference
Upcoming Meetings:
Led by: Bincy Abraham, MD, Kerri Glassner, MD, Malcolm Irani, MD and Christopher Fan, MD
Upcoming Dates:
Dec. 6
Contact: Alessandra Rodriguez for more information.
Medical Center Motility Meeting
First Wednesday of the month from 5-6 p.m.
Multi-institutional conference with The University of Texas MD Anderson Cancer Center, Houston Methodist, UT Health, Baylor College of Medicine.
Contact: Carol Cox (ccox@mdanderson.org) for more information.
SHARE YOUR FEEDBACK
To be featured in the next newsletter, please submit news, events or a story to: underwoodcenter@houstonmethodist.org
If you have questions about membership, please contact: schui@houstonmethodist.org
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