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Spotlight
Funding
Houston Methodist is proud to recognize our highly talented scientists who have been awarded extramural funding this year.
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John Cooke, MD, PhD, Joseph C. “Rusty” Walter and Carole Walter Looke Presidential Distinguished Chair in Cardiovascular Disease Research, Chair, Department of Cardiovascular Sciences, was awarded $216,155 from the Biomedical Advanced Research and Development Authority (BARDA) for a subcontract with Natures ToolBox on a project titled, “Demonstration of a Novel, Rapidly Deployable mRNA Vaccine Production Platform.”
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Cesar Arias, PhD, John F. III and Ann H. Bookout Distinguished Chair for Research Excellence and Co-director, Center for Infectious Diseases Research, Professor of Medicine, was awarded $687,709 from the National Institute of Allergy and Infectious Diseases for the first fiscal year of an R01 titled, “Clinical Impact of the Cefazolin Inoculum Effect.”
Alessandro Grattoni, PhD, Frank J. and Jean Raymond Centennial Chair, Professor of Nanomedicine, was awarded $830,671 from the National Institute of Allergy and Infectious Diseases for the first fiscal year of an R01 titled, “Long-acting multi prevention implant for 2-year contraception and HIV PrEP.”
Philip Horner, PhD, Scientific Director, Center for Neuroregeneration, Professor of Neuroregeneration, was awarded $22,000 from the National Institute of Neurological Disorders and Stroke for an R13 titled, “Patricia Levy Zusman International Workshop on Neuroregeneration.”
Chih-Chi Andrew Hu, PhD, Professor of Cancer Biology in Medicine, was awarded $492,142 from the National Cancer Institute for the first fiscal year of an R01 titled, “Mechanisms of STING in malignant progression and therapy of CLL.”
Rose Khavari, MD, Ben and Wendy Moreland Distinguished Professor in Urology, was awarded $401,219 from the National Institute of Diabetes and Digestive and Kidney Diseases for the first fiscal year of an R01 titled, “A randomized, sham-controlled clinical trial evaluating individualized neuromodulation of cortical regions involved in neurogenic overactive bladder in Multiple Sclerosis.”
Yong Lu, PhD, Associate Professor of Immunology in Medicine, was awarded $583,266 from the National Cancer Institute for the first fiscal year of an R01 titled, “Induction of autosis to overcome resistance in adoptive cell therapy for solid tumors.”
William Miller, MD, Assistant Professor of Medicine, was awarded $171,697 from the National Institute of Allergy and Infectious Diseases for the first fiscal year of an R21 titled, “Emergence of TonB-dependent receptor mediated cefiderocol resistance among multidrug-resistant (MDR) Pseudomonas aeruginosa clinical isolates.”
Henry Pownall, PhD, Sanford I. Weill and Antonio M. Gotto, Jr., MD Centennial Chair in Translational Biomedical Sciences Education, Professor of Biochemistry in Medicine, was awarded $765,547 from the National Heart Lung and Blood Institute for the first fiscal year of an R01 titled, “Human Atherogenesis with Underlying Dysfunctional HDL-Free Cholesterol.”
Miguel Valderrabano, MD, Lois and Carl Davis Centennial Chair I, DeBakey Heart & Vascular Center, Professor of Cardiology, was awarded $738,259 from the National Heart Lung and Blood Institute for an R61 titled, “Venous Ethanol Ablation in Ischemic Ventricular Tachycardia- Velvet Trial.
Miguel Valderrabano, MD, Lois and Carl Davis Centennial Chair I, DeBakey Heart & Vascular Center, Professor of Cardiology, was awarded $ 802,991 from the National Heart Lung and Blood Institute for the first fiscal year of an R01 titled, “Cardiac Autonomic Activation In Atrial Fibrillation Triggers And Substrate.”
Jin Wang, PhD, Professor of Transplant Immunology in Surgery, was awarded $609,170 from the National Institute of Allergy and Infectious Diseases for the first fiscal year of an R01 titled, “Regulation of Cell Death in HIV Reservoirs.”
Alireza Faridar MD, Assistant Professor of Neurology, was awarded $651,539 from the National institute on Aging for the first fiscal year of an R01 titled, “Central and peripheral immune cross-talk in Alzheimer's disease and their modulation by a novel immunotherapy.”
Alessandro Grattoni, PhD, Frank J. and Jean Raymond Centennial Chair, Professor of Nanomedicine, and Norma Sue Kenyon, PhD, Deputy Director and the Martin Kleiman Professor of Surgery, Microbiology and Immunology and Biomedical Engineering at the Diabetes Research Institute, Leonard M. Miller School of Medicine, University of Miami, were awarded $798,092 from the National Institute of Diabetes and Digestive and Kidney Diseases for the first fiscal year of an R01 titled “Vascularized NICHE with local immunosuppression for cell replacement for Type 1 diabetes.”
Hina Faisal, MD, Assistant Professor of Clinical Surgery, was awarded $161,500 from the National Institute on Aging for the first fiscal year of an R03 titled, “Virtual Reality-Based Cognitive Intervention for The Prevention of Delirium & Cognitive Impairment in Geriatric Surgical Patients.”
Bulent Ozpolat, MD, PhD, Research Scientist of Nanomedicine was awarded $377,538 from the National Cancer Institute for the first fiscal year of an R01 titled, “Novel Targeted Therapeutics for Breast Cancer.”
Amy Waterman, PhD, Director, Patient Engagement, Diversity, and Education, Professor of Outcomes Research in Surgery, was awarded $399,999 from the NIH Agency for Healthcare Research and Quality for the first fiscal year of an R01 titled, “Multilevel Intervention Strategies to Transform Kidney Care and Improve Pursuit of Transplant in an Integrated Healthcare Delivery System.”
Yong Lu, PhD, Associate Professor of Immunology in Medicine, was awarded $449,180 from the National Cancer Institute for the first fiscal year of an R01 titled, “Intrapleural Immunotherapeutic Nanoparticles for MPE Treatment.”
Kristopher Brannan, PhD, Assistant Professor of Cardiovascular Sciences, was awarded $249,264 from the National Institute of Neurological Disorders and Stroke for the first fiscal year of a K22 titled, “Exploring Functional Complexes and Disease Networks Within Human RNA-binding Protein Interactomes.”
Gavin Britz, MD, Candy and Tom Knudson Distinguished Centennial Chair in Neurosurgery, Co-director, Center for Translational Neural Prosthetics and Interfaces, Co-director, Center for Neuroregeneration, Director, Neurological Institute, Professor of Neurosurgery, and Angelique Regnier-Golanov, PhD, were awarded $444,125 from the National Institute of Neurological Disorders and Stroke for the first fiscal year of an R21 titled, “Methods and Devices to Assist and Improve Cerebrospinal Fluid Drainage.”
LaShara Davis, PhD, Assistant Professor of Outcomes Research, was awarded $75,000 from the National Kidney Foundation for a Kidney Health Equity Community Engagement Award for the project titled, “Connecting the Dots: Using Digital Storytelling to Educate the African American Community About the Link Between Diabetes, Hypertension and Kidney Disease.”
Alessandro Grattoni, PhD, Frank J. and Jean Raymond Centennial Chair, Professor of Nanomedicine, was awarded $710,235 from the Juvenile Diabetes Research Foundation for a Strategic Research agreement project titled, “Investigation of Novel Local Immunomodulating Strategies to Enhance Islet Transplantation for T1D.”
Alessandro Grattoni, PhD, Frank J. and Jean Raymond Centennial Chair, Professor of Nanomedicine, and Joan Nichols, PhD, Dr. and Mrs. Alan L. Kaplan Centennial Professor in Cellular Therapeutics and Organ Bioengineering, Professor of Immunology in Surgery, were awarded $712,661 from the National Institute of Diabetes and Digestive and Kidney Diseases for the first fiscal year of an R01 titled, “Vascularized Islet transplantation NICHE with local immunosuppression for the treatment of type 1 diabetes.”
Shannan Hamlin, PhD, RN, Director, Center for Nursing Research, Education and Practice, Associate Professor of Nursing, was awarded $28,238 for a project titled, “The Future of Robot-Assisted Nursing: Interactive AI Frameworks for Upskilling Nurses and Customizing Robot Assistance.”
Philip Horner, PhD, Scientific Director, Center for Neuroregeneration, Professor of Neuroregeneration, and Matthew Hogan, PhD, were awarded $228,034 from Wings for Life for a project titled, “Neuromodulation for Enhanced Functional Integration of Alginate Encapsulated Pre-organized and Networked Neural Stem Cell Ribbon Grafts.”
Philip Horner, PhD, Scientific Director, Center for Neuroregeneration, Professor of Neuroregeneration, was awarded $176,569 from the National Institute of Neurological Disorders and Stroke for the first fiscal year of a T32 titled, “Training in Neural Control of organ Degeneration and Regeneration (NeuralCODR).”
Robert Krencik, PhD, Assistant Professor of Neurosurgery, was awarded $100,000 from the Institute for Rehabilitation and Research Foundation for the project titled, “AstroCapsules: A Novel Tool to Detect and Modulate the Neurotrauma Microenvironment.”
Alessandro Grattoni, PhD, Frank J. and Jean Raymond Centennial Chair, Professor of Nanomedicine, was awarded $808,087 from the National Institute of Allergy and Infectious Diseases for the first fiscal year of an R01 titled, “Ultra-long Acting Transcutaneously Refillable Islatravir Nanofluidic Implant for HIV Pre-Exposure.”
Kai Sun, MD, was awarded $50,000 from the American Society of Clinical Oncology for a project titled, “Targeting Nitric Oxide Synthase Pathway in Obesity-Associated Triple Negative Breast Cancer.”
Rajarajan Amirthalingam Thandavarayan, PhD, Assistant Research Professor of Cardiology, was awarded $295,817 from the American Heart Association for a Transformational Project Award titled, “Role of CstF64 Mediated Alternative Polyadenylation in Heart Failure.”
Cesar Arias, MD, PhD, John F. III and Ann H. Bookout Distinguished Chair for Research Excellence and Co-director, Center for Infectious Diseases Research, Professor of Medicine, was awarded $ 2,411,532 from the National Institute of Allergy and Infectious Diseases for the first fiscal year of a PO1 titled, “Dynamics of Colonization and Infection by Multidrug-resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE).”