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Active/Enrolling Clinical Trials
June 2024

The Underwood Center reviews this list of active/enrolling clinical trials before publication. However, the status of the studies may change. Please contact the study coordinator to inquire about enrollment for your patient.
Disease/Condition
Cirrhosis
PI
Victor, David
Particulars of Eligible Patient Population
Cirrhosis
Intervention
Rifaximin
Contact
Nikki Hinton nhinton@houstonmethodist.org
Disease/Condition
Gastroparesis
PI
Dacha, Sunil
Particulars of Eligible Patient Population
Gastroparesis and non-gastroparesis patients scheduled for upper endoscopy
Intervention
EndoFLIP device
Contact
Melissa Whipple, mbwhipple@houstonmethodist.org
Disease/Condition
GERD
PI
Kim, Min
Particulars of Eligible Patient Population
Gastroesophageal Reflux Disease
Intervention
LINX Reflux Management System
Contact
Danika Nottage dlnottage@houstonmethodist.org
Disease/Condition
HCC
PI
Victor, David
Particulars of Eligible Patient Population
Cirrhosis & early HCC
Intervention
N/A - Biomarker study
Contact
Ahmed Elsaiey, aelsaiey@houstonmethodist.org
Disease/Condition
IBD
PI
Abraham, Bincy
Particulars of Eligible Patient Population
Pregnant women with IBD and their infants through 18 years old that have been exposed to a biologic, small molecule, or immunomodulator at any time through delivery.
Intervention
N/A - Registry study with questionnaires and blood samples
Contact
Melissa Whipple, mbwhipple@houstonmethodist.org
Disease/Condition
IBD-Arthropathy
PI
Abraham, Bincy
Particulars of Eligible Patient Population
IBD Arthropathy with active joint symptoms who would be treated with celecoxib as SOC
Intervention
Curcumin vs Celecoxib
Contact
Melissa Whipple, mbwhipple@houstonmethodist.org
Disease/Condition
NASH
PI
Victor, David
Particulars of Eligible Patient Population
Compensated cirrhosis due to NASH (F4)
Intervention
BMS-986263 vs placebo
Contact
Miguel Valdivia y Alvarado mvaldiviayalvarado@houstonmethodist.org
Disease/Condition
NASH
PI
Victor, David
Particulars of Eligible Patient Population
NASH (NAS > 4) with liver fibrosis (F2-F3)
Intervention
Semaglutide vs placebo
Contact
Nikki Hinton, nhinton@houstonmethodist.org
Disease/Condition
NASH
PI
Victor, David
Particulars of Eligible Patient Population
NASH with liver fibrosis F2-F3)
Intervention
Lanifibranor vs placebo
Contact
Miguel Valdivia y Alvarado, mvaldiviayalvarado@houstonmethodist.org
Disease/Condition
NASH
PI
Victor, David
Particulars of Eligible Patient Population
NASH with Compensated Sirrhosis (F4) due to Nonalcoholic Steatohepatitis (NASH)
Intervention
Cilofexor with Firsocostat
Contact
Nikki Hinton nhinton@houstonmethodist.org
Disease/Condition
NASH
PI
Victor, David
Particulars of Eligible Patient Population
Nonalcoholic Steatohepatitis (NASH)
Intervention
Resmetirom
Contact
Nikki Hinton nhinton@houstonmethodist.org
Disease/Condition
PBC
PI
Victor, David
Particulars of Eligible Patient Population
Primary Biliary Cholangitis
Intervention
Bezafibrate with Obeticholic Acid
Contact
Nikki Hinton nhinton@houstonmethodist.org
Disease/Condition
Ulcerative Colitis
PI
Abraham, Bincy
Particulars of Eligible Patient Population
Moderately to Severely Active Ulcerative Colitis
Intervention
ABX464 (Obefazimod)
Contact
Melissa Whipple mbwhipple@houstonmethodist.org
Disease/Condition
Ulcerative Colitis
PI
Abraham, Bincy
Particulars of Eligible Patient Population
Moderately to Severely Active Ulcerative Colitis
Intervention
ABX464 (Obefazimod)
Contact
Melissa Whipple mbwhipple@houstonmethodist.org
Disease/Condition
Celiac Disease
PI
Quigley, Eamonn
Particulars of Eligible Patient Population
Active Celiac Disease
Intervention
TAK-062
Contact
Melissa Whipple mbwhipple@houstonmethodist.org
Disease/Condition
Diabetic Gastroparesis
PI
Quigley, Eamonn
Particulars of Eligible Patient Population
Diabetic Gastroparesis
Intervention
CIN-102
Contact
Melissa Whipple mbwhipple@houstonmethodist.org
Disease/Condition
HCC
PI
Abdelrahim, Maen
Particulars of Eligible Patient Population
HCC
Intervention
Lenvima plus TACE or TARE
Contact
Miguel Valdivia y Alvarado mvaldiviayalvarado@houstonmethodist.org
Disease/Condition
HCC
PI
Abdelrahim, Maen
Particulars of Eligible Patient Population
HCC
Intervention
Atezolizumab and Bevacizumab
Contact
Miguel Valdivia y Alvarado mvaldiviayalvarado@houstonmethodist.org
Disease/Condition
HCC
PI
Abdelrahim, Maen
Particulars of Eligible Patient Population
HCC
Intervention
Atezolizumab and Bevacizumab
Contact
Miguel Valdivia y Alvarado mvaldiviayalvarado@houstonmethodist.org
Disease/Condition
Ulcerative Colitis
PI
Abraham, Bincy
Particulars of Eligible Patient Population
Moderate to Severely Active Ulcerative Colitis
Intervention
ozanimod
Contact
Melissa Whipple mbwhipple@houstonmethodist.org
Disease/Condition
c. Diff
PI
Fan, Christopher
Particulars of Eligible Patient Population
Recurrent c. Diff infections receiving REBYOTA as per SOC
Intervention
REBYOTA as per SOC
Contact
Davesia Tenner dtenner@houstonmethodist.org
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